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Ultimate Metabolic Formula

(8 customer reviews)

Systemic Enzyme Formula Supports:

  • Healthy Joint Function*
  • Healthy Sports Recovery*
  • Fibrin Metabolism*

  90 Capsules:  $49.99  Now $39.99
200 Capsules: $89.95 Now $79.99


Ultimate Metabolic Formula – (Exclzyme® 2AF)

Joint, Muscle & Tissue Health

An extra-strength systemic enzyme blend formulated to help support healthy joint, muscle and tissue function.*

Why Take Ultimate Metabolic Formula

The Ultimate Metabolic Formula is a clinically-proven blend of proteolytic enzymes, herbs, vitamins and minerals for powerful joint, muscle and tissue support.*

This specially formulated enzyme blend supports:

  • Healthy Joint Function*
  • Sports Recovery*
  • Fibrin Metabolism*
  • Muscle, Joint and Tissue Health*
  • Healthy Antioxidant Levels*
  • Immune Health*
  • Healthy Blood Circulation*


What’s Inside Ultimate Metabolic Formula
In addition to papain and bromelain, Ultimate Metabolic Formula features acid-resistant serrapeptase (Peptizyme SP® EN), a systemic enzyme known for its capacity to support normal fibrin levels and promote healthy circulation.*

Research and clinical studies consistently show serrapeptase can help break down dead cells produced as a result of the inflammatory process. By breaking down cellular debris, serrapeptase promotes circulation, allowing vital nutrients and building blocks to nourish new cells.*

In addition to serrapeptase and other enzymes, Ultimate Metabolic Formula also contains the potent herbs boswellia and turmeric, as well as vitamin C, amla, rutin and grape seed extract for antioxidant support.*

 How MAAC Acid-Resistant Polymer Makes Ultimate Metabolic Formula Uniquely Effective

Your stomach is naturally acidic to help digest food. But not every supplement can tolerate that acidity. Some enzymes, like serrapeptase, are powerful but delicate. They need a special delivery system that helps protect them from stomach acid. The cutting-edge, phthalate-free, methyacrylic acid copolymer (MAAC) applied to the Peptizyme SP® EN in Ultimate Metabolic Formula increases potency by allowing more enzyme activity to pass through the stomach, delivering it into the small intestine, where it is most needed.

When evaluated by an independent third-party laboratory, the MAAC-containing Peptizyme SP® EN used in Ultimate Metabolic Formula was found to have enzyme activity significantly greater than regular serrapeptase after passing through the acidic conditions of the stomach, allowing for much greater efficacy.

MAAC is a food-grade compound that has been in use as an enteric coating in the pharmaceutical industry for over 50 years with no reported side effects. In fact, the European Food Safety Authority – an organization that conducted studies which led to the ban of six types of phthalates in personal care products in Europe in 2004 – has deemed MAAC safe for use as a coating agent in food supplements. 

As a science-first company, AST Enzymes uses acid-resistant Peptizyme SP® EN because it delivers the best enzymes in their best form.

 Why Choose Ultimate Metabolic Formula

Ultimate Metabolic Formula’s clinically proven, extra-strength blend and efficacy-maximizing acid-resistant polymer application give it unrivaled joint support properties.* It is manufactured in ISO 9001:2000 and NSF-GMP certified facilities and undergoes rigorous quality testing.

What Isn’t Inside Ultimate Metabolic Formula

Ultimate Metabolic Formula is free of pesticides, chemicals, preservatives, animal derivatives, dairy, yeast, fish or shellfish, peanuts, and tree nuts. All individual enzymes are kosher-certified ingredients, and suitable for vegetarians and vegans.

Ultimate Metabolic Formula is manufactured in the USA in NSF-certified facilities that follow cGMP guidelines, for the highest quality products.

How to Take Ultimate Metabolic Formula

Take with 8 oz. of water on an empty stomach (30-60 minutes before or 2 hours after meals).

Begin by taking 1 to 2 capsules three times a day. In three days, if the desired benefit is not achieved, increase to 2 to 3 capsules three times a day.

Store in cool, dry place with the lid tightly closed. Avoid excessive heat. Keep out of the reach of children.

Caution: If you are pregnant, nursing, taking any medication or under medical supervision, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

SKU: N/A Category:

Directions: Take 1 to 2 capsules three times a day on an empty stomach. In three days, if desired benefit is not achieved, increase to 2 to 3 capsules three times a day. Take capsules at least 30 to 60 minutes before or 2 hours after a meal with 8 oz. of water. Store in cool, dry place with the lid tightly closed. Avoid excessive heat. Keep out of the reach of children.

Caution: If you are pregnant, nursing, taking any medication or under medical supervision, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Not intended for use by persons under the age of 18.


Are there any side effects involved with Ultimate Metabolic Formula?

The use of Ultimate Metabolic Formula has not been shown to exhibit detrimental effects, long term or short term. Just as dosage requirements vary, minor side effects may vary. Although gastrointestinal disturbances have been reported by a small percentage of new users, tolerance is maintained once the dosage is adjusted. Minor allergic reactions, like reddening of the skin, are also rare occurrences, and can be seen with extremely high doses. There are no known interactions with prescription or over the counter drugs while using systemic enzyme therapy. However, it is recommended that you consult with your physician about starting systemic enzymes, particularly if you are on blood-thinning medications, or are pregnant or nursing.

Can I take Ultimate Metabolic Formula with other systemic enzymes?

Systemic enzymes may be taken together, yielding desirable results, as long as they are taken on an empty stomach. In fact, it is often recommended that systemic enzymes be combined. Products like Ultimate Metabolic Formula and Peptizyme-SP® often have synergistic effects when taken together. This means that the separate products work together to produce advantageous results. By combining and enhancing the activity of the enzymes, their effects on the healing process are more attainable.

Can I take Ultimate Metabolic Formula with digestive enzymes?

Although digestive and systemic enzymes are not contraindicated in terms of ingredients, they cannot be taken at the same time. The purpose of digestive enzymes is to aid in digestion of specific foods, so taking them with food is an obvious recommendation. Because systemic enzymes require an empty stomach for maximum absorption, they must be taken separately from digestive enzymes. There are no adverse interactions between systemic and digestive enzymes, but they serve different purposes and thus should be taken as directed for best results.

Does Ultimate Metabolic Formula have acid-resistance?

Yes, an acid-resistant polymer is applied to the serrapeptase in Ultimate Metabolic Formula. While similar systemic enzymes may have the same active ingredients, most do not apply such a polymer. The purpose of this acid-resistant polymer is to protect the enzyme from the acidic environment of the stomach. When an acid-resistant polymer is applied to the enzymes, its activity is more likely to be preserved until it reaches the small intestine, where absorption into the bloodstream takes place. While this polymer can withstand the acidic environment of the stomach, the alkaline environment of the small intestine will disintegrate this polymer, allowing the enzyme to be active within the bloodstream.

Based on 8 reviews

5.0 overall

Add a review

  1. Janet

    I love AST and the great products and service I receive. Since systemic enzymes are so beneficial for overall health and are natural, they are perfect to compliment one’s health. They contribute to keeping me healthy, active and feeling good. If there are times I am not feeling as good as usual, I slow down, get more rest, and up the enzyme intake a little. Before long, I am back to feeling great with more energy.

  2. Cynthia Macavoy (verified owner)

    We have used these enzymes for several years now with great success. They are our first line of defense for inflammation so we take them religiously. The formulation is well thought out with herbals added in for added inflammation support. We are grateful.

  3. Marge Lewis

    I have been buying the Ultimate Metabolic formula for over 3 years now and I trust the product that AST provides. I know by body doesn’t produce the enzymes it did when I was younger and believe they are vital to me leading and living and active & healthy life physically. Inflammation is the source of many conditions and I certainly want to do what I can to ward them off!

  4. Christine Parrott

    Awesome product great against joint pain and inflammation.

  5. Rich Menard (verified owner)

    Exclyzme-2AF with the Vitamin B coenzyme (Now Ultimate Metabolic Formula) is a great combination with many benefits. Helps with recovery, sports performance, and digestive balance. Taken as part of workout regiment (pre/post) and pre-meal to support immune and digestive health, they’ve improved my overall sense of well-being…I love AST Enzyme products. I have been supplementing with the Vida Defense as well for several months now and my digestive balance is the best it’s been in years. I have the least inflammation and most energy in a long time. For over a year now, I have been working out 1-2 hours a day and these systemic enzymes are critical to recovery and balance and give me the added support I need.

  6. Shannah Beukema (verified owner)

    I have been using this and other AST products for the past year and my ability to process problematic foods has improved. I am so glad I heard about this from a caller who was a doctor who recommended it to his patients on a Coast 2 Coast am radio show for systemic support.

  7. Barbara Peden

    We started to use the AST Metabolic Formula recently as they were recommended by friends who have found them very helpful. They have become part of our daily health care routine. I have noticed more energy, and less inflammation. We also have been using the Floracor-GI which has helped with digestive issues. Thanks!!

  8. Melony (verified owner)

    I’ve noticed a huge improvement in my overall wellness…including a boost of energy, better digestion and the need to share with everyone I know. My friends and family all report feeling the best they’ve ever felt adding AST enzymes to their vitamin supplements -especially this one in particular!

Buy These Products Together and Save

  • Ultimate Metabolic Formula + Floracor-GI + FREE Digest-GI

    Total Price $135.98
    Add all 3 to cart

    Buy Floracor-GI with Ultimate Metabolic Formula to Support Absorption

    Floracor-GI with Ultimate Metabolic Formula together provide even greater benefits. One of our most popular blends, Floracor-GI is a blend of probiotics, prebiotics and powerful enzymes to support gastrointestinal health, microflora balance and immune health.

    Combining Floracor-GI with the powerful systemic enzymes in Ultimate Metabolic Formula supports systemic enzymes therapy, and joint and muscle health.

    FREE Digest-GI WITH PURCHASE! – A $29.99 Value

    DigeSEB-GI is a broad-spectrum digestive enzyme blend to support digestion of all types of foods.

    1 Ultimate Metabolic Formula (200 caps.) + 1 Floracor-GI (180 caps.) + 1 Digest-GI (90 caps.)= $175.93 NOW $145.94


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