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Nattokinase Supports:

  • Cardiovascular Health*
  • Healthy Blood Flow*
  • Circulatory Health*
  • Healthy Fibrin Levels*

  60 Capsules: $24.99 Now $19.99


A powerful systemic enzyme to support healthy cardiovascular, circulatory & respiratory systems.*

Why Take Nattokinase

Nattokinase supports respiratory and sinus health, and promotes cardiovascular and circulatory health.*

The ingredient in this powerful enzyme blend support:

  • Cardiovascular Health*
  • Normal Circulation*
  • Respiratory Health*
  • Healthy Lung Function*

What’s Inside Nattokinase

  • Enteric coated Nattokinase 2,000 FU per capsule

What Isn’t Inside Nattokinase

Nattokinase is free of pesticides, chemicals, preservatives, animal derivatives, dairy, yeast, fish or shellfish, peanuts, and tree nuts. All individual enzymes are kosher-certified ingredients, and suitable for vegetarians and vegans.

Nattokinase is manufactured in the USA and follows cGMP guidelines, for the highest quality products.

What is Nattokinase?

Nattokinase is a fibrinolytic enzyme belonging to the serine protease class. It was originally found in natto, a Japanese fermented soybean breakfast dish and traditionally used to support heart health.

Why Take Fibrinolytic Enzymes?

Imagine you scrape your knee – your blood immediately clots and your body makes a scaffolding out of fibrin (a thread-like protein) to hold the clot in place. This acts as a natural bandage as the body heals. Your body uses fibrin to repair internal injuries too.

But your body also has to take down the fibrin scaffolding (a process called fibrinolysis). Your body naturally does this with an enzyme called plasmin, which breaks down the fibrin into parts the body can process. Healthy fibrinolysis is critical to manage pain, scarring and potential blood clots.

Fibrinolytic enzymes are proteases that break down the tough strings of fibrin protein. Supplementing with fibrinolytic enzymes can help your body maintain healthy fibrin metabolism.*

How to Take Nattokinase

Take on an empty stomach (30-60 minutes before or 2 hours after meals).

  •  Take 1-2 capsules daily with a large glass of water.

Caution: If you are pregnant, nursing, taking any medication or under medical supervision, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

SKU: N/A Category:
Directions: Take 1-2 capsules daily
with a large glass of water.
Take on an empty stomach (30 to 60
minutes before or 2 hours after a meal.


What is systemic enzyme therapy?

Systemic enzyme therapy refers to the therapeutic use of enzymes to support healthy cardiovascular, respiratory, immune systems, among others. Systemic enzymes are absorbed from the small intestine where they enter the bloodstream and execute their effects on the entire body as a system.

What is a systemic proteolytic enzyme?

Proteolytic enzymes break down proteins into their building-blocks, which are called amino acids. Systemic proteolytic enzymes are responsible for breaking down accumulated protein and waste substances found in the circulatory system and connective tissue.

How long should I take Nattokinase before feeling results?

The length of time to experience the benefits of systemic enzymes varies by individual. Some people notice a difference within days. For others, it’s a week or 10 days. For long-term benefits, it’s important to take systemic enzymes consistently over several months.

New systemic enzyme users should start off slow, with one capsule, daily. After three to four days of proven tolerance, the dose can be increased to a 2 capsules daily.  Monitored, and dosage should be adjusted accordingly.  There are several factors that may affect required dosage, including:

  • Height
  • Weight
  • Age
  • Tolerance
  • Time of administration (Better absorbed on an empty stomach)
  • Adherence to regimen
  • Nutritional state

What if I miss a dose?

Regular, consistent use of systemic enzymes will provide the best results, however missed doses of systemic enzymes do not have serious repercussions. Although symptoms alleviated by systemic enzyme therapy may resurface, getting back on track by remembering to take your next dose will suffice. There is also the option of incorporating another dose during the day. There is no need to “double up” on one dose. Also remember, systemic enzymes are best absorbed on an empty stomach.

Why is it important to take Nattokinase on an empty stomach?

Since most absorption occurs in the small intestine, the systemic enzymes survive the stomach intact. If enzymes are taken with food, they will likely begin working to break down your food within the stomach, rather than passing through to the small intestine. Taking systemic enzymes like Nattokinase with food will compromise their absorption, as well as their effectiveness.

Are there any side effects involved with Nattokinase?

The use of Nattokinase has not been shown to exhibit detrimental effects, long term or short term. Minor side effects may vary. Gastrointestinal disturbances have been reported by a small percentage of new users, but once the dosage is adjusted, tolerance is maintained. Minor allergic reactions, like reddening of the skin, are also rare occurrences, and can be seen with extremely high doses. There are no known interactions with prescription or over the counter drugs while using systemic enzyme therapy. However, it is recommended that you consult with your physician about starting systemic enzymes, particularly if you are on blood-thinning medications, or are pregnant or nursing.

Can I take Nattokinase with other systemic or digestive enzymes?

Systemic enzymes may be taken together, yielding desirable results, as long as they are taken on an empty stomach. In fact, it is often recommended that systemic enzymes be combined. Separate blends or enzymes often work together to produce advantageous results. By combining and enhancing the activity of the enzymes, their effects on supporting the body are more attainable.

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