Muscular Skeletal Health
Muscular skeletal discomfort can make everyday life difficult. When that discomfort becomes prolonged, it can manifest into chronic discomfort throughout the body. Seemingly simple day-to-day tasks can become overwhelmingly difficult. Living with chronic muscular skeletal issues can bring daily challenges, including:
- Overall body discomfort
- Difficult mobility
- Psychological stress
- Digestive issues
- Exercise intolerance
Many times, when a system in our body malfunctions, we look for the first source of immediate relief, whether over-the-counter or prescribed. Regular use is often accompanied by side effects.
The Purpose of Enzymes
Enzymes are ubiquitous in nature, and found in every one of our cells. Enzymes are catalysts to begin a chemical reaction or cause it to speed up. About 3,000 enzymes have been identified in the human body. Each works like a lock to a key, and performs a unique function. Enzymes are integral in everything from metabolism to breathing to your heart rate. Without enzymes, life would not exist.
Systemic Enzyme Therapy
Digestive enzymes work in the stomach to support digestion, while systemic enzymes work throughout the body to support the body’s many other functions, muscles, joints, nerves, tissues, etc.* As we age, our body’s production of enzymes may slow down, or we may stop producing specific enzymes. Taking an enzyme supplement supports healthy, normal functioning.
Naturally occurring systemic enzymes provide a non-invasive, natural and effective choice without the negative side effects. Systemic enzymes promote quality of life.
Excellacor & Serrapeptase 80,000 SPU
Excellacor is scientifically formulated to support overall metabolic health, as well as muscle and joint health.* Serrapeptase supports joint, muscle, respiratory, and tissue health.* When taken together, the combination produces a synergistic effect and amplifies their collective beneficial properties.
Excellacor and Serrapeptase 80,000 SPU contain enteric-coated serrapeptase. Enteric coating allows enzymes, which are often sensitive to pH or temperature, bypass the acidic environment of the stomach and survive until they reach the small intestine, where absorption occurs. The efficacy of a systemic enzyme is supported by enteric coating. AST Enzymes’ enteric-coated serrapeptase has been formulated with the use of Methacrylic Acid Copolymer (MAAC), a safe food-grade compound used in the pharmaceutical industry with no reported side effects. Without enteric coating, systemic enzymes can denature in the stomach, and then simply serve as a very expensive digestive enzyme.
The Excellacor formulation has been commercially available for nearly 20 years. This original proprietary formula created by our master enzymologist has been used with much success. Serrapeptase 80,000 SPU is one of the most potent doses of Serrapeptase on the market today.
Our enzymes are manufactured in ISO 9001:2000 and GMP certified facilities, and undergo rigorous quality testing.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat,cure,or prevent any disease.
Excellacor

Directions: Take on an empty stomach (30-60 minutes before or 2 hours after meals).
Day 1-5: Take 1 capsule, 3 times a day.
Day 6-11: Take 2 capsule, 3 times a day.
Day 12+ (if needed): 3(+) capsules, 3 times a day.
Serrapeptase

Directions: Add Serrapeptase to your Excellacor regimen. Take on an empty stomach (30-60 minutes before or 2 hours after meals).
Day 6-11: Take 1 capsule, twice a day.
Day 12+ (if needed): Take 2(+) capsules, twice a day.
Caution If you are pregnant, nursing, taking any medication or under medical supervision, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur.
FAQ
What is systemic enzyme therapy?
Systemic enzyme therapy refers to the therapeutic use of natural enzymes to support numerous systems in the body. Systemic enzymes are absorbed in the small intestine where they enter the bloodstream. Then they carry out desired benefits throughout the body.
What are proteolytic enzymes?
Proteolytic enzymes break down proteins into their building-blocks, which are called amino acids. Systemic proteolytic enzymes are responsible for breaking down accumulated protein and waste substances found in the circulatory system and connective tissue.
Why is it important to take Excellacor and Serrapeptase on an empty stomach?
Since most absorption occurs in the small intestine, the systemic enzymes must bypass the stomach to gain access there. If the enzymes are taken with food, they will likely begin working to break down your food within the stomach, rather than passing through to the small intestine. Taking systemic enzymes like Excellacor with food will compromise their absorption, as well as their effectiveness.
Does Excellacor have an enteric coating?
Yes, the serrapeptase in Excellacor is enterically coated. While similar systemic enzymes may have the same active ingredients, most do not utilize enteric coating. The purpose of enteric coating is to protect the enzyme from the acidic environment of the stomach. High activity level is preserved until the enzymes reach the small intestine, where absorption into the bloodstream takes place. While the enteric coating can withstand the acidic environment of the stomach, the alkaline environment of the small intestine will disintegrate the enteric coating, allowing the enzyme to be active within the bloodstream.
Do you use phthalates in your enteric coating?
No, our enteric coating does not use or contain phthalates. At AST Enzymes, we use Methacrylic Acid Copolymer (MAAC) for our enteric coating. Compared to other commonly used enteric coating agents such as Cellulose Acetate Phthalate (CAP) and Hydroxypropyl Methycellulose Phthalate (HPMCP), MAAC is the most gastro-resistant and does not carry the same risks. Additionally, MAAC is considered GRAS (Generally Recognized as Safe) by the FDA and is approved for use by the European Food Safety Authority. To learn more about enteric coating used in AST Enzymes products, please click the Compare tab.
How long should I take Excellacor before feeling results?
The length of time to experience the benefits of systemic enzymes varies by individual. Some people notice a difference within days. For others, it’s a week or 10 days. For long-term benefits, it’s important to take systemic enzymes consistently over several months. New systemic enzyme users should start off slow, with one capsule, three times daily. After three to four days of proven tolerance, the dose can be increased to a 2 capsules, 3 times per day. Some consumers find their ideal dose between 9-12 capsules per day, while others only need 3-6. There are several factors that may affect required dosage, including:
- Height
- Weight
- Age
- Tolerance
- Time of administration (better absorbed on an empty stomach)
- Adherence to regimen
- Nutritional state
What if I miss a dose?
Regular, consistent use of systemic enzymes will provide the best results. However, missed doses of systemic enzymes do not have serious repercussions. Although symptoms alleviated by systemic enzyme therapy may resurface, getting back on track by remembering to take your next dose will suffice. There is no need to “double up,” on one dose – and remember, systemic enzymes are best absorbed on an empty stomach.
Are there any side effects involved with Excellacor?
The use of Excellacor has not been shown to exhibit detrimental effects, neither long term nor short term. Just as dosage requirements vary, side effects may vary. Although gastrointestinal disturbances have been stated by a small percentage of new users, tolerance is maintained once the dosage is adjusted. Minor allergic reactions, like reddening of the skin, are also rare occurrences, and can be seen with extremely high doses. There are no known interactions with prescription or over the counter drugs while using systemic enzyme therapy. However, it is recommended that you consult with your physician about starting systemic enzymes, especially if you are on blood-thinning medications or if you are pregnant or nursing.
Can I take Excelacor with other systemic enzymes?
Systemic enzymes may be taken together, yielding desirable results, as long as they are taken on an empty stomach. In fact, it is often recommended that systemic enzymes be combined. Products like Excellacor and Serrapeptase often have synergistic effects when taken together. This means that the separate products work together to produce advantageous results. By combining and enhancing the activity of the enzymes, they better support metabolic health.
Can I take Excellacor with digestive enzymes?
Although digestive and systemic enzymes are not contraindicated in terms of ingredients, they cannot be taken at the same time. The purpose of digestive enzymes is to aid in digestion of specific foods, so taking them with food is an obvious recommendation. Because systemic enzymes require an empty stomach for maximum absorption, they must be taken separately from digestive enzymes. There are no adverse interactions between systemic and digestive enzymes, but they serve different purposes and thus should be taken as directed for best results.
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