Excellacor- The Original Systemic Formula
(Exclzyme- Same Exact Formula, New Name!)
The Purpose of Enzymes
The human body produces enzymes responsible to support all biological reactions within the body. Enzymes are found in every cell of every living being. The different systems in our bodies including our cardiovascular, digestive, and immune systems, would not be able to function without the support of these proteolytic enzymes. Enzymes carry out chemical reactions necessary for simple everyday functions such as our metabolism, breathing, and even our heart rate. As we age, our bodies gradually become less efficient, producing significantly fewer enzymes. When this occurs, it is imperative for us to supplement with necessary enzymes to prevent havoc.
Everybody Needs a Healthy Body
Elimination of potentially toxic substances from the body is a crucial part in the metabolic processes for optimal health. While eliminating these toxins is the body’s natural response, sometimes it can be a difficult task. A variety of health issues can develop if toxins within the body impair enzyme function availability or without a proper store of enzymes.
For instance, the immune system can be overwhelmed with bacteria, fungi, toxins and even food particles that do not get completely digested in the gastro-intestinal tract. The body is then filled with proteins created by these distresses. The body detects these particles as foreign and initiate an immune response. Recognized as antigens, the immune system produces antibodies to start the process to remove these foreign substances. After coupling with one another, these antigens and antibodies form circulating immune complexes (CICs) and lead to a burden on our immune system.
When this occurs, the body does not produce an adequate amount of proteolytic enzymes to attack the large accumulation of CIC’s. While enzymes occur naturally, our bodies may not produce an adequate amount. Supplementing the body with enzymes becomes crucial to prevent further complications. Enzymes serve as catalysts that push essential chemical reactions in the body in the right direction. Without proper supplementation, the body will lose its internal balance.
Systemic Enzyme Therapy
For nearly 40 years, serrapeptase has been at the heart of Systemic Enzyme Therapy –the use and supplementation of systemic enzymes like serrapeptase for optimal cell, tissue, organ and metabolic function. Likewise, companies, health practitioners, and consumers have turned to the original Exclzyme formulation for their systemic enzyme therapy needs.
The reality is that inflammation affects everyone, and nearly all tissues and organs in the body. Although inflammation in each case may manifest differently, inflammation still has one thing in common: fibrin.
Fibrin is an essential protein that is produced during inflammation. It is the initial first step in the body’s attempts at recovery. However, when inflammation has become prolonged, fibrin along with other proteins such as collagen can begin to transform original tissue into a tough fibrous matrix. Differentiated and sometimes sequestered apart from healthy tissue, this fibrous matrix still has the biological markers of inflammation. Nutrients, and other building blocks are still needed for healthy normal tissue.
Excellacor® for Total Body Support*
The Excellacor formulation has been commercially available for nearly 20 years. It is the #1 non-animal derived systemic formulation to date. Our original proprietary formula, created by our master enzymologist, has been used with much success. Likewise, companies, health practitioners, and consumers have turned to the original Excellacor formulation for their systemic enzyme therapy needs.
Excellacor contains enteric-coated serrapeptase, a key ingredient in fibrin metabolism. The enteric-coated allows the enzymes to bypass the acidic environment of the stomach and reach the small intestine, where absorption occurs. This is a key factor to determine the efficiency of any systemic enzyme. Our enteric-coated serrapeptase has been formulated with the use of Methacrylic Acid Copolymer (MAAC), a safe food-grade compound used in the pharmaceutical industry with no reported side effects. Without enteric coating, enzymes will denature in the stomach, and simply be a really expensive digestive enzyme.
In addition, various proteases in Excellacor help break down proteins and amino acid chains, promoting total body support. The combination of its key ingredients work synergistically as a potent systemic enzyme blend. This formula supports fatigued muscles and joint function, and promotes fibrin metabolism.*
Key Ingredients in Excellacor:
- Enteric-coated Serrapeptase (phthalate Free): a Powerful fibrinolytic enzyme.*
- Bromelain: derived from pineapple, supports healthy circulation.*
- Papain: derived from papaya, supports protein digestion and the body’s natural immune response.*
- Lipase: used systemically, supports the break down fats into essential fatty acids. Supports healthy circulation.*
- Amylase: for added synergistic support; breaks down carbohydrates and starches (found in human tissue) into simple sugars*
- Rutin: a bioflavonoid that supports against free radicals*
- Amla: natural source of Vitamin C, supports regulatory immune responses.*
This blend also offers its own enzyme activity to bolster the body with extra catalytic energy. Excellacor is rounded with anti-oxidant support in the form of herbs known for their unique ability to enhance Vitamins. This anti-oxidant support is especially useful for tissue rejuvenation and recovery.* Our systemic enzyme blend is manufactured in a ISO 9001:2000 and GMP certified facility.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat,cure,or prevent any disease.
Excellacor (formerly known as Exclzyme) vs Vitalzym**
||Enteric Coated Serrapeptase
||Serrapeptase Manufacturing Source
|Original Vitalzym (2000-2009)
|“Original” Vitalzym (Current)
|Vitalzym 360 Liquid Capsules (Current)
If your systemic enzyme supplement has changed, we have the original formula.
Some companies claim to continue to carry the original formula. One easy way to check is to see if the bottle says the enzyme serrapeptase is enteric-coated. Serrapeptase, sourced from the bacterium Serratia marcescens is the key ingredient in the original Full-Strength Excellacor. This key ingredient must be enteric coated so it can pass through the acid environment of the stomach without being damaged.
And as for the new formulas on the market claiming to be stronger or more technologically advanced: the proof is in the results.
There is an underlying art when it comes to manufacturing enzyme products. Systemic enzyme blends must be formulated professionally for maximum effectiveness. In fact, alterations to an already successful systemic enzyme product may not provide the same results you’ve come to expect.
Many companies, including ours, use proprietary formulas to protect their products from being copied and used by others. But all companies must list all of the ingredients by name, and rank the ingredients according to the percentage amounts in the formula. For instance, in the original Excellacor formula, enteric-coated serrapeptase is listed on our ingredient list as the second most prevalent ingredient in our formulation.
If your “new and improved” systemic formula does not list enteric coated serrapeptase as the second ingredient, you are probably not getting the most out of your systemic enzyme formula. Serrapeptase has always been the hallmark of the original Excellacor formula, making it the choice of companies and consumers alike.
Enteric Coating Comparison
||Methacrylic Acid Copolymer
Cellulose Acetate Phthalate (CAP)
|Hydroxypropyl Methylcellulose Phthalate (HPMCP)
|Considered Enteric Coating
|Studies supporting Efficacy as Enteric Coating
|Time in Use
*AST Enzymes uses MAAC as enteric coating
What is enteric coating, and why is it needed?
Enteric coating is a layer of protective coating to allow supplements to bypass digestion by the stomach and be absorbed in the small intestine. Systemic enzymes are proteins, so their functional structures are denatured (or destroyed) in conditions of extreme pH and temperature. Without enteric coating, enzymes would be rendered useless long before they reach the bloodstream, where they carry out their beneficial effects.
What’s enteric coating made of?
At AST Enzymes, we use Methacrylic Acid Copolymer (MAAC) for our enteric coating. Methacrylic Acid Copolymer (MAAC) is not a phthalate. According to independent studies, MAAC is the most gastro-resistant when compared to other commonly used enteric coating agents such as Cellulose Acetate Phthalate (CAP) and Hydroxypropyl Methycellulose Phthalate (HPMCP). This means that MAAC can most effectively withstand the acidity of the stomach, allowing its contents to be released in the small intestine and fully absorbed.
Don’t let the name scare you. MAAC is a food-grade compound that has been in use as enteric coating in the pharmaceutical industry for over 50 years with no reported side effects. In 2004, the European Food Safety Authority – an organization that conducted studies which led to the ban of 6 types of phthalates in personal care products– has deemed MAAC safe for use as coating agent in food supplements.
MAAC is listed as Generally Recognized As Safe (GRAS) by the Food and Drug Administration (FDA). The Environmental Protection Agency (EPA) also conducted various studies and found sufficient information to reasonably conclude that the current use pattern of MAAC will not adversely affect public health or the environment.
** Vitalzym® is a registered trademark of World Nutrition Inc., which is not affiliated with, nor sponsors or endorses this product or any other product from Specialty Enzymes & Biotechnologies or AST Enzymes.
What is systemic enzyme therapy?
Systemic enzyme therapy refers to the therapeutic use of natural enzymes to produce desired healing effects. Systemic enzymes are absorbed in the small intestine where they enter the bloodstream. Then they carry out desired benefits throughout the body.
What are proteolytic enzymes?
Proteolytic enzymes break down proteins into their building-blocks, which are called amino acids. Systemic proteolytic enzymes are responsible for breaking down accumulated protein and waste substances found in the circulatory system and connective tissue. Regular systemic proteolytic enzyme use can improve circulation.*
What is fibrin?
Fibrin is a protein-based substance that is needed to help blood coagulation, playing a substantial role in immune response. When the body responds to injury or chronic inflammation, fibrin is recruited to the damaged area to form scar tissue. Although the body is equipped with plasmin, a naturally occurring enzyme responsible for breaking down excess fibrin, plasmin levels progressively decrease as we age. This actually increases the risk for excessive, undesirable scar tissue formation in the body.
Why is it important to take Excellacor on an empty stomach?
Since most absorption occurs in the small intestine, the systemic enzymes must bypass the stomach to gain access there. If the enzymes are taken with food, they will likely begin working to break down your food within the stomach, rather than passing through to the small intestine. Taking systemic enzymes like Excellacor with food will compromise their absorption, as well as their effectiveness.
Does Excellacor have an enteric coating?
Yes, the serrapeptase in Excellacor is enterically coated. While similar systemic enzymes may have the same active ingredients, most do not utilize enteric coating. The purpose of enteric coating is to protect the enzyme from the acidic environment of the stomach. High activity level is preserved until the enzymes reach the small intestine, where absorption into the bloodstream takes place. While the enteric coating can withstand the acidic environment of the stomach, the alkaline environment of the small intestine will disintegrate the enteric coating, allowing the enzyme to be active within the bloodstream.
Do you use phthalates in your enteric coating?
No, our enteric coating does not use or contain phthalates. At AST Enzymes, we use Methacrylic Acid Copolymer (MAAC) for our enteric coating. Compared to other commonly used enteric coating agents such as Cellulose Acetate Phthalate (CAP) and Hydroxypropyl Methycellulose Phthalate (HPMCP), MAAC is the most gastro-resistant and does not carry the same risks. Additionally, MAAC is considered GRAS (Generally Recognized as Safe) by the FDA and is approved for use by the European Food Safety Authority. To learn more about enteric coating used in AST Enzymes products, please click the Compare tab.
How long should I take Excellacor before feeling results?
Since people experience varying ailments and severity of disease, the length of time to include systemic enzymes in your regimen may vary as well. As an overall guideline, it is typically recommended that new systemic enzyme users start off slow. A starter dose is generally one capsule, three times daily. After three to four days of proven tolerance, the dose can be increased to a therapeutic dose of 3 capsules, 3 times per day. At this point, results may be monitored, and dosage should be adjusted accordingly. Some consumers find their therapeutic dose between 9-15 capsules per day, while others only need 3-6. There are several factors that may affect results and required dosage, including:
- Severity of symptoms
- Time of administration (Better absorbed on an empty stomach)
- Adherence to regimen
- Nutritional state
What if I miss a dose?
Regular, consistent use of systemic enzymes will provide the best results. However, missed doses of systemic enzymes do not have serious repercussions. Although symptoms alleviated by systemic enzyme therapy may resurface, getting back on track by remembering to take your next dose will suffice. There is no need to “double up,” on one dose – and remember, systemic enzymes are best absorbed on an empty stomach.
Are there any side effects involved with Excellacor?
The use of Excellacor has not been shown to exhibit detrimental effects, neither long term nor short term. Just as dosage requirements vary, side effects may vary. Although gastrointestinal disturbances have been stated by a small percentage of new users, tolerance is maintained once the dosage is adjusted. Minor allergic reactions, like reddening of the skin, are also rare occurrences, and can be seen with extremely high doses. There are no known interactions with prescription or over the counter drugs while using systemic enzyme therapy. However, it is recommended that you consult with your physician about starting systemic enzymes, especially if you are on blood-thinning medications or if you are pregnant or nursing.
Can I take Excelacor with other systemic enzymes?
Systemic enzymes may be taken together, yielding desirable results, as long as they are taken on an empty stomach. In fact, it is often recommended that systemic enzymes be combined. Products like Excellacor and Serrapeptase often have synergistic effects when taken together. This means that the separate products work together to produce advantageous results. By combining and enhancing the activity of the enzymes, their effects on the healing process are more attainable.
Can I take Excellacor with digestive enzymes?
Although digestive and systemic enzymes are not contraindicated in terms of ingredients, they cannot be taken at the same time. The purpose of digestive enzymes is to aid in digestion of specific foods, so taking them with food is an obvious recommendation. Because systemic enzymes require an empty stomach for maximum absorption, they must be taken separately from digestive enzymes. There are no adverse interactions between systemic and digestive enzymes, but they serve different purposes and thus should be taken as directed for best results.